Pharmacogenomics of amlodipine and hydrochlorothiazide therapy and the quest for improved control of hypertension: a mini review

R Johnson, P Dludla, S Mabhida, M Benjeddou… - Heart failure …, 2019 - Springer
… CYP3A5 does not affect the pharmacokinetic variability of amlodipine [22… ABCB1 gene (also
known as multi drug resistance 1; MDR1) … The haplotype analysis data suggested that SNPs …

WAYS AND PROSPECTS OF IMPROVING THE EFFECTIVENESS AND SAFETY OF PHARMACOTHERAPY OF CHRONIC GASTRITIS

GSPD Ochilova - Journal of Pharmaceutical Negative Results, 2022 - pnrjournal.com
… of this protein determines the pharmacokinetics of drugs and, … of polymorphisms C3435T,
G2677T, C1236T of the MDR1 gene … Patients with genotypic affiliation with / T made up a huge …

Efficacy and Safety of Pharmacotherapy of Chronic Gastritis

OG Saidovna, OA Kamilovich - Academia Open, 2022 - acopen.umsida.ac.id
… essential for comprehending drug pharmacokinetics and optimizing … of polymorphisms
C3435T, G2677T, C1236T of the MDR1Patients with genotypic affiliation with / T made up a huge …

Pharmacokinetic drug interactions between amlodipine, valsartan, and rosuvastatin in healthy volunteers

SJ Seong, B Ohk, WY Kang, MR Gwon, BK Kim… - Advances in …, 2019 - Springer
… The transporter involved in the efflux of amlodipine is multidrug resistance 1 (MDR1) and …
24 h after dosing, and additional 48- and 72-h visits were made for pharmacokinetic sampling. …

DIFFERENTIATED APPROACH TO THE TREATMENT OF CHRONIC GASTRITIS, TAKING INTO ACCOUNT GENETIC MARKERS

GS Ochilova - EUROPEAN JOURNAL OF MODERN MEDICINE AND …, 2022 - inovatus.es
patients to improve pharmacotherapy with chronic gastritis by the MDR1 gene, which provides
the pharmacokinetics … our results and the data obtained by the standardized test system of …

… coupled to LC-MS/MS for simultaneous determination of amlodipine, olmesartan and hydrochlorothiazide in plasma samples: Application to pharmacokinetic studies

EF Elkady, AA Mandour, FK Algethami… - Microchemical …, 2020 - Elsevier
… Drug-free K 3 EDTA human plasma samples were harvested on-site from healthy volunteers
Similarly the deduced pharmacokinetic parameters of HCT came in close agreement with …

Association of variants in the ABCB1, CYP2C19 and CYP2C9 genes for Juvenile Myoclonic Epilepsy

A Jara-Prado, JL Guerrero-Camacho… - Neurological …, 2024 - Springer
… , are caused by their reactive metabolites derived from their transformation by metabolizing
… of ABCB1 show great interindividual and interethnic variation, whose CGC haplotype (1236/…

The Importance of Genotyping Patients with Chronic Gastritis by the MDR-1 Gene

GS Ochilova - KRS Journal of Medicine, 2022 - krsjournal.com
… Kim KA, Park PW, Park JY Effect of ABCB1 (MDR1) haplotypes derived from G2677T/C3435T
on the pharmacokinetics of amlodipine in healthy subjects//Br. J. Clin.…

ABCG2 Single Nucleotide Polymorphism Affects Imatinib Pharmacokinetics in Lower Alpha-1-Acid Glycoprotein Levels in Humans

JW Park, H Chung, KA Kim, JM Kim, IH Park… - Frontiers in …, 2021 - frontiersin.org
pharmacokinetics in a controlled study of healthy subjects. We hypothesized that the effect of
ABCG2 and ABCB1 … the ABCG2 and ABCB1 genotypes, a blood sample was obtained from …

[HTML][HTML] Pharmacogenomics-based individualized treatment of hypertension in preterm infants: A case report and review of the literature

LF Tang, A Xu, K Liu - World Journal of Clinical Cases, 2023 - ncbi.nlm.nih.gov
… The ABCB1 gene of the antihypertensive drug amlodipine also … cause differences in
pharmacokinetics, efficacy, and side effects. It … that in healthy individuals, those with the ABCB1